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Boletín de novedades
Julio - Agosto 2016
Nano - Medicina
Julio - Agosto 2016
Boletín de novedades
Índice
PUBLICACIONES CIENTÍFICAS
Index-Report-FLAG
1. Cultivo a corto plazo de monocitos como sistema de evaluación in vitro para nanobiomateriales d...
2
2. Fabricación de andamio de nanocompuestos a base de hidrogel con nanopartículas de vidrio bioact...
2
3. Aplicación de familia de nanopartículas de sílice mesoporoso en el teranóstico de cáncer
3
4. Formulación de nanomedicinas para el tratamiento de tuberculosis
3
5. Biosensores ópticos basados en nanoestructuras de ZnO: ventajas y perspectivas
4
6. Nanopartículas multifuncionales a base de aptámeros para la administración dirigida de fármacos...
4
PATENTES
7. Nano-puntos de polímero conjugado como rastreadores de células madre a largo plazo
5
8. Material de relleno óseo
5
9. Detección, medición e imagen de células y otras substancias biológicas utilizando nanopartícula...
6
10. Diagnóstico de nanopartículas y métodos para el tratamiento de enfermedad
6
11. Dispositivo para administración de fármacos utilizada para la artritis reumatoide
7
NOTICIAS
12. Nanovacuna podría mejorar la inmunoterapia del cáncer con menores efectos secundarios
8
13. Nanopartículas derivadas del jengibre potenciales medicinas para enfermedades inflamatorias del...
8
14. Investigadores desarrollan nuevos agentes nanorobóticos para la administración de fármacos foca...
8
15. Nueva nanomedicina para el cáncer reduce el crecimiento de tumores pancreáticos
9
16. £1.2 millones para microesferas inyectables que transportan células madre para regenerar los hu...
9
17. "Hilo inteligente" permite la incrustación de tejidos 3D para el diagnóstico médico
10
18. Precision NanoSystems lanza sistema de nanomedicina para el desarrollo terapéutico
11
Julio - Agosto 2016
Boletín de novedades
Índice
19. Nuevas tecnologías a nanoescala mejoran resultados de imágenes en microscopios comunes
11
20. Nanopartículas tolerogénicas podrian detener la diabetes
12
21. Nuevo libro científico destaca avances y desafíos en el desarrollo de nanoteranóstica para la m...
12
22. Ingenieros desarrollan nuevo chip biosensor para detectar mutaciones del ADN
13
23. Nueva herramienta nanobiotecnológica de prognosis para el cáncer cerebral
13
MERCADO
24. Mercado global de nanobiotecnología 2015-2021
14
25. Tendencias, tecnología y análisis del mercado global de nano terapia - Pronóstico para el 2027
14
26. Análisis y tendencias del mercado global de nanomedicina - Pronóstico de la industria para el 2...
14
27. Industria global de implantes dentales
15
28. Nanoarquitectura para para la administración y liberación inteligente de fármacos
15
29. Nanopartículas de óxido de lantánido para imágenes biomédicas y terapia
15
EVENTOS
30. Conferencia internacional sobre nanomedicina y nanobiotecnología – ICONAN 2016.
16
Pág. 2
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
PUBLICACIONES CIENTÍFICAS
Cultivo a corto plazo de monocitos como sistema de evaluación in
vitro para nanobiomateriales designados para uso médico
Publicada en Science Direct- Nano-Medicina-Equipos Médicos, 25/08/2016
Publication date: 21 August 2016 Source:Food and Chemical Toxicology Author(s):
Ekaterina Igorevna Shishatskaya, Dragana Nikitovic, Alexander Shabanov
Vasilievich, George N. Tzanakakis, Aristidis M. Tsatsakis, Natalia Gennadievna
Menzianova We studied the feasibility of using a short-term culture of monocytes,
isolated from peripheral donor blood, to assess the biological activity of different
types of bionanomaterials (BNM): biodegradable polimeric particles, fiber and film
substrates of micro- and nano-dimensions, fullerenes (F) and nanodiamonds (ND),
which are either currently in use and/or potentially applicable in medicine.
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Fabricación de andamio de nanocompuestos a base de hidrogel con
nanopartículas de vidrio bioactivo para la ingeniería de tejidos del
miocardio
Publicada en Science Direct- Publicaciones Científicas sobre Nano-Medicina-Tratamiento,
18/08/2016
Publication date: 1 December 2016 Source:Materials Science and Engineering: C,
Volume 69 Author(s): Zahra Barabadi, Mahmoud Azami, Esmaeel Sharifi, Roya
Karimi, Nasrin Lotfibakhshaiesh, Reza Roozafzoon, Mohammad Taghi Joghataei,
Jafar Ai Selecting suitable cell sources and angiogenesis induction are two important
issues in myocardial tissue engineering. Human endometrial stromal cells (EnSCs)
have been introduced as an abundant and easily available resource in regenerative
medicine. Bioactive glass is an agent that induces angiogenesis and has been
studied in some experiments.
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Pág. 3
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Aplicación de familia de nanopartículas de sílice mesoporoso en el
teranóstico de cáncer
Publicada en Science Direct- Publicaciones Científicas sobre Nano-Medicina-Tratamiento,
15/07/2016
Publication date: 15 July 2016 Source: Coordination Chemistry Reviews, Volume
319 Author(s): Yin Feng, Nishtha Panwar, Danny Jian Hang Tng, Swee Chuan Tjin,
Kuan Wang, Ken-Tye Yong Cancer is among the most serious diseases
characterized by uncontrollable cell growth and spread of abnormal cells. Cancerous
cells form tumors that negatively impact the functions of the body, inducing serious
malfunctioning leading to fatalities in most cases. Up to now, the effective diagnosis
and treatments of cancer have remained a big challenge. Nanotechnology is an
emerging field encompassing science, engineering and medicine, which has
attracted great attention for cancer therapy in recent years.
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Formulación de nanomedicinas para el tratamiento de tuberculosis
Publicada en Science Direct- Publicaciones Científicas sobre Nano-Medicina-Tratamiento,
01/07/2016
Publication date: 1 July 2016 Source: Advanced Drug Delivery Reviews, Volume 102
Author(s): Ana Costa, Marina Pinheiro, Joana Magalhães, Ricardo Ribeiro, Vitor
Seabra, Salette Reis, Bruno Sarmento Recent estimates indicate that tuberculosis
(TB) is the leading cause of death worldwide, alongside the human
immunodeficiency virus (HIV) infection. The current treatment is effective, but is
associated with severe adverse-effects and noncompliance to prescribed regimens.
An alternative route of drug delivery may improve the performance of existing drugs,
which may have a key importance in TB control and eradication.
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Pág. 4
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Biosensores ópticos basados en nanoestructuras de ZnO: ventajas y
perspectivas
Publicada en Science Direct- Nano-Medicina- Prevención y Diagnóstico, 28/06/2016
Publication date: 28 June 2016 Source:Sensors and Actuators B: Chemical, Volume
229 Author(s): Alla Tereshchenko, Mikhael Bechelany, Roman Viter, Volodymyr
Khranovskyy, Valentyn Smyntyna, Nikolay Starodub, Rositza Yakimova This review
article highlights the application of beneficial physico-chemical properties of ZnO
nanostructures for the detection of wide range of biological compounds. As the
medical diagnostics require accurate, fast and inexpensive biosensors, the
advantages inherent optical methods of detection are considered.
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Nanopartículas multifuncionales a base de aptámeros para la
administración dirigida de fármacospara evitar la resistencia al cáncer
Publicada en Science Direct- Publicaciones Científicas sobre Nano-Medicina-Tratamiento,
01/06/2016
Publication date: June 2016 Source: Biomaterials, Volume 91 Author(s): Juan Liu,
Tuo Wei, Jing Zhao, Yuanyu Huang, Hua Deng, Anil Kumar, Chenxuan Wang, Zicai
Liang, Xiaowei Ma, Xing-Jie Liang By its unique advantages over traditional
medicine, nanomedicine has offered new strategies for cancer treatment. In
particular, the development of drug delivery strategies has focused on nanoscale
particles to improve bioavailability. However, many of these nanoparticles are unable
to overcome tumor resistance to chemotherapeutic agents. Recently, new
opportunities for drug delivery have been provided by oligonucleotides that can selfassemble into three-dimensional nanostructures. In this work, we have designed and
developed functional DNA nanostructures to deliver the chemotherapy drug
doxorubicin (Dox) to resistant cancer cells.
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Pág. 5
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
PATENTES
Nano-puntos de polímero conjugado como rastreadores de células
madre a largo plazo
Publicada en Patentscope - Patentes sobre Nano-Medicina - Equipos Médicos, 26/08/2016
This invention relates to a method for tracking stem cells characterized in that the
stems cells are labelled with at least one fluorescent conjugated polymer nanodot
and the fluorescence of the labelled cells is detected. The fluorescent conjugated
polymer nanodot comprises a conjugated polymer such as poly(9,9-dihexylfluorenealt-2,1,3-benzoxadiazole) (PFBD) capped with an amphiphilic co-polymer such as
DSPE-PEG2000 (1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)conjugated polyethylene glycol) and DSPE-PEG2000 maleimide.
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Material de relleno óseo
Publicada en Patentscope - Patentes sobre Nano-Medicina - Tratamiento 1, 11/07/2016
Group of inventions relates to porous two-phased calcium phosphate/hydroxyapatite (FK/GAP) material proposed as
substitute bone containing sintered FK rod and at least one homogeneous and closed epitaxic grown layer of nanocrystalline GAP applied on top of sintered FK rod, wherein epitaxic grown nano-crystals have same size and structure,
such as human bone mineral, i.e. length making 30-46 nm, and width making 14-22 nm, which is impregnated with
collagen fibres at weight ratio of said collagen fibres to said porous calcium phosphate /hydroxyapatite (FK/GAP) material
proposed as substitute bone of at least 2 %.
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Pág. 6
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Detección, medición e imagen de células y otras substancias
biológicas utilizando nanopartículas dirigidas y propiedades
magnéticas de las mismas
Publicada en Patentscope - Patentes sobre Nano-Medicina - Equipos Médicos, 28/06/2016
Invention relates to medicine, namely, to the means of detecting and measuring cells or substances via targeted
nanoparticles. Apparatus comprises a magnetizing subsystem for magnetization nanoparticles which are associated with
one or more specified types of cancer cells, or biological substances in a patient, a sensor subsystem to detect the
residual magnetic field in the region of interest of the patient after the unbound nanoparticles back to the random
magnetization, and for a time nanoparticles of transition related to the random homogeneous magnetization, and the
management and analysis of the residual magnetic field to detect, measure or determine the location of one or more
specific types of cancer cells, or biological substances in a patient.
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Diagnóstico de nanopartículas y métodos para el tratamiento de
enfermedad
Publicada en Patentscope - Patentes sobre Nano-Medicina - Prevención y Diagnóstico 2,
17/06/2016
The present invention relates to the use of in vivo contrast agents in medical imaging
in order to diagnose and treat disease, and to monitor and assess disease
progression following treatment with a nanoparticle therapeutic agent comprising an
active pharmaceutical agent. The present invention also relates to modulating
nanoparticle tumor concentration by modulating the PEG density of the
nanoparticles.
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Pág. 7
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Dispositivo para administración de fármacos utilizada para la artritis
reumatoide
Publicada en Patentscope - Patentes sobre Nano-Medicina - Equipos Médicos, 28/05/2016
Group of inventions relates to medicine. Application describes an apparatus and method for delivering a drug in
rheumatoid arthritis through the dermal barrier, and a method of manufacturing the device. Apparatus includes
microneedles for penetrating the stratum corneum and also includes structures made on the surface of the microneedles
for forming nanotopography. Can be made arbitrary or ordered pattern of structures such as sophisticated pattern
comprising structures of different sizes and/or shapes.
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Pág. 8
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
NOTICIAS
Nanovacuna podría mejorar la inmunoterapia del cáncer con menores
efectos secundarios
Publicada en Nano Magazine - Nanotechnology News, 24/08/2016
Researchers have created a nanovaccine that could make a current approach to
cancer immunotherapy more effective while also reducing side effects.
ver más...
Nanopartículas derivadas del jengibre potenciales medicinas para
enfermedades inflamatorias del intestino
Publicada en EIN - Nanotechnology News Today - Nanotechnology Research News,
18/08/2016
A recent study by researchers at the Atlanta Veterans Affairs Medical Center took them to a not-so-likely destination:
local farmers markets. They went in search of fresh ginger root.
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Pág. 9
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Investigadores desarrollan nuevos agentes nanorobóticos para la
administración de fármacos focalizada en tumores cancerosos
Publicada en EIN - Nanotechnology News Today - Nanotechnology Research News,
16/08/2016
Researchers from Polytechnique Montréal, Université de Montréal and McGill University have just achieved a spectacular
breakthrough in cancer research. They have developed new nanorobotic agents capable of navigating through the
bloodstream to administer a drug with precision by specifically targeting the active cancerous cells of tumours.
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Nueva nanomedicina para el cáncer reduce el crecimiento de tumores
pancreáticos
Publicada en PhysOrg.com - Bio & Medicine News, 08/08/2016
Australian cancer researchers have developed a highly promising nanomedicine that
could improve treatment for pancreatic cancer – the most deadly cancer in Australia.
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Pág. 10
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
£1.2 millones para microesferas inyectables que transportan células
madre para regenerar los huesos
Publicada en EurekAlert! - Nanotechnology News, 25/07/2016
The University of Nottingham has secured £1.2m to develop injectable stem cellcarrying materials to treat and prevent fractures caused by osteoporosis and other
bone-thinning diseases.
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"Hilo inteligente" permite la incrustación de tejidos 3D para el
diagnóstico médico
Publicada en EIN - Nanotechnology News Today - Nanotechnology Research News,
21/07/2016
By integrating microfluidic networks, nano-scale sensors, and electronics,
researchers have created implantable, thread-like devices that can be sutured
through several layers of tissue in 3-D to gather and send diagnostic data wirelessly
as it happens.
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Pág. 11
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Precision NanoSystems lanza sistema de nanomedicina para el
desarrollo terapéutico
Publicada en EIN - Nanotechnology News Today - Nanotechnology Conference News,
20/07/2016
Precision NanoSystems Inc. announces the launch of the NanoAssemblr Spark
system to support nanoparticle researchers developing novel nucleic acid-based
nanomedicines, including mRNA and CRISPR/Cas9 therapeutics. The
NanoAssemblr Spark enables automated microfluidic manufacture of nanoparticles
at ultra-low volumes for rapid and cost-effective early-stage nanomedicine discovery
and development.
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Nuevas tecnologías a nanoescala mejoran resultados de imágenes en
microscopios comunes
Publicada en AZoNano.com_Nanomedicine | News Feed, 20/07/2016
Chemists, biologists, and engineers from the University of Missouri have conducted
research that could change the way scientists analyze cells and molecules at submicroscopic (nanoscale) levels.
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Pág. 12
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Nanopartículas tolerogénicas podrian detener la diabetes
Publicada en NanotechWeb_Tech update - Nanotechnology News, 29/06/2016
Researchers in the US have developed nanoparticles that could halt autoimmune
diseases like type I diabetes. The particles carry two main components: a small
molecule that induces immune tolerance and a peptide that is normally attacked by
the body’s autoimmune response.
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Nuevo libro científico destaca avances y desafíos en el desarrollo de
nanoteranóstica para la medicina personalizada
Publicada en AZoNano.com_Nanomedicine | News Feed, 24/06/2016
Nanomedicines demonstrate the capability to enhance drug properties by offering
protection from degradation, Nanomedicines demonstrate the capability to enhance
drug properties by offering protection from degradation, enabling controlled release
and biodistribution and increasing bioavailability.
enabling controlled release and biodistribution and increasing bioavailability. In
fact,...
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Pág. 13
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Ingenieros desarrollan nuevo chip biosensor para detectar
mutaciones del ADN
Publicada en ScienceDaily_ Nanotechnology News, 14/06/2016
An electrical graphene chip capable of detecting mutations in DNA has been
developed by engineers. The researchers say the technology could one day be used
in various medical applications such as blood-based tests for early cancer screening,
monitoring disease biomarkers and real-time detection of viral and microbial
sequences.
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Nueva herramienta nanobiotecnológica de prognosis para el cáncer
cerebral
Publicada en ScienceDaily_ Nanotechnology News, 13/06/2016
A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells
migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.
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Pág. 14
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
MERCADO
Mercado global de nanobiotecnología 2015-2021
Publicada en EIN - Nanotechnology News Today - Nanotechnology Research News,
23/08/2016
… .researchandmarkets.com/research/2wt8fp/nanobiotechnology Related Topics: Diagnostics, Drug Delivery, Drug
Discovery, Nanotechnology, Nanomedicine Media Contact: Research and Markets Laura Wood, Senior Manager
press@researchandmarkets …
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Tendencias, tecnología y análisis del mercado global de nano terapia Pronóstico para el 2027
Publicada en EIN - Nanotechnology News Today - Nanotechnology Conference News,
05/08/2016
Global Nano therapy Market Information by technology (Nanomaterial and biological device, Nano electronic biosensor)
by disease medication - Forecast to 2027
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Análisis y tendencias del mercado global de nanomedicina Pronóstico de la industria para el 2025
Publicada en EIN - Nanotechnology News Today - Nanomedicine News, 03/08/2016
The Global Nanomedicine Market is poised to grow at a CAGR of around 16.6% over the next decade to reach
approximately $1.3 trillion by 2025.
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Pág. 15
Julio - Agosto 2016
Boletín de novedades
Nano - Medicina
Industria global de implantes dentales
Publicada en EIN - Nanotechnology News Today - Nanotechnology Research News,
25/07/2016
This report analyzes the worldwide markets for Dental Implants in US$ Million. The report provides separate
comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual
estimates and forecasts are provided for the period 2015 through 2022.
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Nanoarquitectura para para la administración y liberación inteligente
de fármacos
Publicada en Research and Markets - Nanotechnology Market Publications, 24/07/2016
Nanoarchitectonics for Smart Delivery and Drug Targeting is one of the first on the market to exclusively focus on
nanoarchitectonics in its entirety.
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Nanopartículas de óxido de lantánido para imágenes biomédicas y
terapia
Publicada en Research and Markets - Nanotechnology Market Publications, 29/06/2016
Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide
Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular
imaging and therapeutics.
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Pág. 16
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Boletín de novedades
Nano - Medicina
EVENTOS
Conferencia internacional sobre nanomedicina y nanobiotecnología –
ICONAN 2016.
Publicada en NANOfutures - Nanotechnology Upcoming Events, 25/07/2016
September 28- 30, 2016. Paris, France. The International Conference On
Nanomedicine And Nanobiotechnology is an annual event that hosts high-profile
plenary speakers, world class researchers, oral and poster presentations,
workshops, sponsor exhibits and afterworks.
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Para más información:
Programa Nacional de Vigilancia Tecnológica e Inteligencia Competitiva (VINTEC)
Dirección Nacional de Estudios (DNE) · Subsecretaría de Estudios y Prospectiva
Ministerio de Ciencia, Tecnología e Innovación Productiva de la Nación
Godoy Cruz 2320 3 piso · (C1425FQD) · Buenos Aires · Argentina
Tel: (011) 4899-5300 int. 3004 · vintec@mincyt.gob.ar · www.mincyt.gob.ar
Entidades que colaboraron:
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