Document related concepts
Transcript
NanoAntilatHIV: Development of a new drug/nucleic acid nanocarrier against HIV-1 latency ADRESSED PATHOLOGY: HIV-1 Infection GENERAL OBJECTIVES: Development of a new therapeutic strategy against HIV-1 infection which avoids the toxicity and resistances of the actual drugs (antiretrovirals). This new approach reduces the size of the latent reservoirs of human immunodeficiency virus type 1 (HIV-1) in infected cells by means the design of a novel nanosystem able to act in a combined therapy based on the codelivery of drugs and nucleic acids into the infected cells. PARTICIPANTS: — — — — Blanca González/María Vallet, GIBI-UCM, Universidad Complutense de Madrid. Francisco Javier de la Mata, GDAB-UAH, Universidad de Alcalá de Henares. María Ángeles Muñoz, Muñoz LIBM-HGUGM, LIBM-HGUGM Hospital General Universitario Gregorio Marañón. Marañón Ramón Eritja, GQNA-CSIC, Instituto de Química Avanzada de Cataluña.