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EYE-PoC Point Of Care Biosensor Devices To Detect Biomarkers As Evaluation End-Points For Therapeutic Clinical Trials In Ocular Surface Inflammation ADRESSED PATHOLOGY: Dry-eye Disease (DED) GENERAL OBJECTIVES: Development D l t off specific ifi and d sensitive iti point-of-care i t f (P C) biosensor (PoC) bi d i devices ( l t (electrochemical h i l and optical), based on protein or gene specific expression in tears and/or conjunctival epithelial cells, to be used as evaluation end-points in clinical trials to detect activity/therapeutic biomarkers for ocular surface inflammatory diseases. PARTICIPANTS: — — — — Amalia Enríquez-de-Salamanca/ Margarita Calonge /Itziar Fernández/ María J G González-García ál G í (also ( l clinical li i l group), ) IOBA-Uva IOBA U group, University U i it off Valladolid. V ll d lid Pilar Marco, Roger Galve, Enrique Valera, Javier Ramón. NB4D-CSIC, Instituto de Química Avanzada de Cataluña. Laura Lechuga/Daphne Duval, CIN2-CSIC, Centro de Investigación en Nanociencia y Nanotecnología, Barcelona. Ramon Eritja/ Ana Aviñó GQNA-CSIC, Instituto de Química Avanzada de Cataluña.